流体二元脂质混合物中三相或两相终点的路径依赖性。
Path dependence of three-phase or two-phase end points in fluid binary lipid mixtures.
作者信息
Lamberson Emily R, Cambrea Lee R, Rochet Jean-Christophe, Hovis Jennifer S
机构信息
Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA.
出版信息
J Phys Chem B. 2009 Mar 19;113(11):3431-6. doi: 10.1021/jp810326w.
Abstract
The phase behavior of anionic/zwitterionic mixtures can be controlled by tuning the charge state of the anionic lipid. In the case of dioleoylphosphatidic acid (DOPA)/dioleoylphosphatidylcholine (DOPC) mixtures, demixing occurs either when DOPA is protonated or when DOPA(2-):Ca(2+) complexes form. Herein it will be shown that the final end point, a three-phase or two-phase system, depends on the order in which the charge state is manipulated. The facile accessibility of different end points is a clear demonstration of the inherent flexibility of biological systems.
摘要
阴离子/两性离子混合物的相行为可通过调节阴离子脂质的电荷状态来控制。在二油酰磷脂酸（DOPA）/二油酰磷脂酰胆碱（DOPC）混合物的情况下，当DOPA质子化或形成DOPA(2 -):Ca(2 +)络合物时会发生相分离。本文将表明，最终终点，即三相或两相系统，取决于操纵电荷状态的顺序。不同终点的易达性清楚地证明了生物系统固有的灵活性。
相似文献
1
Path dependence of three-phase or two-phase end points in fluid binary lipid mixtures.流体二元脂质混合物中三相或两相终点的路径依赖性。
J Phys Chem B. 2009 Mar 19;113(11):3431-6. doi: 10.1021/jp810326w.
2
Effect of doxorubicin on the order of the acyl chains of anionic and zwitterionic phospholipids in liquid-crystalline mixed model membranes: absence of drug-induced segregation of lipids into extended domains.阿霉素对液晶混合模型膜中阴离子和两性离子磷脂酰基链排列顺序的影响：不存在药物诱导的脂质分离成扩展结构域的现象。
Biochemistry. 1992 Sep 29;31(38):9252-62. doi: 10.1021/bi00153a019.
3
Effect of ions on the organization of phosphatidylcholine/phosphatidic acid bilayers.
Biophys J. 2007 Sep 1;93(5):1630-8. doi: 10.1529/biophysj.107.104224. Epub 2007 May 4.
4
Agonist binding and affinity state transitions in reconstituted nicotinic acetylcholine receptors revealed by single and sequential mixing stopped-flow fluorescence spectroscopies.
Biochim Biophys Acta. 1998 Sep 23;1374(1-2):83-93. doi: 10.1016/s0005-2736(98)00133-3.
5
Controlling the charge and organization of anionic lipid bilayers: effect of monovalent and divalent ions.控制阴离子脂质双层的电荷与组织：单价和二价离子的作用
J Phys Chem B. 2007 Dec 13;111(49):13664-7. doi: 10.1021/jp076306a. Epub 2007 Nov 15.
6
Effects of aromatic residues at the ends of transmembrane alpha-helices on helix interactions with lipid bilayers.跨膜α螺旋末端芳香族残基对螺旋与脂质双层相互作用的影响。
Biochemistry. 2000 Feb 29;39(8):2071-8. doi: 10.1021/bi992205u.
7
Surface charge markedly attenuates the nonlamellar phase-forming propensities of lipid bilayer membranes: calorimetric and (31)P-nuclear magnetic resonance studies of mixtures of cationic, anionic, and zwitterionic lipids.表面电荷显著减弱脂质双层膜形成非片层相的倾向：阳离子、阴离子和两性离子脂质混合物的量热法和³¹P核磁共振研究
Biophys J. 2000 Sep;79(3):1455-64. doi: 10.1016/S0006-3495(00)76397-1.
8
Coexistence of two liquid crystalline phases in dihydrosphingomyelin and dioleoylphosphatidylcholine binary mixtures.二氢鞘磷脂与二油酰磷脂酰胆碱二元混合物中两种液晶相的共存。
Biochim Biophys Acta. 2014 May;1838(5):1372-81. doi: 10.1016/j.bbamem.2014.01.017. Epub 2014 Jan 24.
9
Effects of phospholipid headgroup and phase on the activity of diacylglycerol kinase of Escherichia coli.磷脂头部基团和相态对大肠杆菌二酰基甘油激酶活性的影响
Biochemistry. 2001 Dec 11;40(49):14891-7. doi: 10.1021/bi011333r.
10
Effect of peptide length on the interaction between consensus peptides and DOPC/DOPA bilayers.
Langmuir. 2006 May 23;22(11):5042-50. doi: 10.1021/la060317y.
引用本文的文献
1
Adsorption of alpha-synuclein on lipid bilayers: modulating the structure and stability of protein assemblies.α-突触核蛋白在脂质双层上的吸附：调节蛋白质组装体的结构和稳定性。
J Phys Chem B. 2010 Mar 25;114(11):4070-81. doi: 10.1021/jp1006704.
本文引用的文献
1
Electrostatic behavior of the charge-regulated bacterial cell surface.电荷调节细菌细胞表面的静电行为。
Langmuir. 2008 May 6;24(9):5003-9. doi: 10.1021/la703564q. Epub 2008 Mar 26.
2
Controlling the charge and organization of anionic lipid bilayers: effect of monovalent and divalent ions.控制阴离子脂质双层的电荷与组织：单价和二价离子的作用
J Phys Chem B. 2007 Dec 13;111(49):13664-7. doi: 10.1021/jp076306a. Epub 2007 Nov 15.
3
Phospholipase D activity is regulated by product segregation and the structure formation of phosphatidic acid within model membranes.磷脂酶D的活性受模型膜内产物分离和磷脂酸结构形成的调控。
Biophys J. 2007 Oct 1;93(7):2373-83. doi: 10.1529/biophysj.107.108787. Epub 2007 Jun 8.
4
Effect of ions on the organization of phosphatidylcholine/phosphatidic acid bilayers.
Biophys J. 2007 Sep 1;93(5):1630-8. doi: 10.1529/biophysj.107.104224. Epub 2007 May 4.
5
Phosphatidic acid domains in membranes: effect of divalent counterions.膜中的磷脂酸结构域：二价抗衡离子的影响。
Biophys J. 2007 Apr 15;92(8):2806-18. doi: 10.1529/biophysj.106.092015. Epub 2007 Jan 26.
6
A modified Poisson-Boltzmann model including charge regulation for the adsorption of ionizable polyelectrolytes to charged interfaces, applied to lysozyme adsorption on silica.一种改进的泊松-玻尔兹曼模型，包括用于可电离聚电解质吸附到带电界面的电荷调节，应用于溶菌酶在二氧化硅上的吸附。
J Phys Chem B. 2005 Mar 10;109(9):4172-80. doi: 10.1021/jp0463823.
7
Why pH titration in protein solutions follows a Hofmeister series.为何蛋白质溶液中的pH滴定遵循霍夫迈斯特序列。
J Phys Chem B. 2006 Apr 13;110(14):7563-6. doi: 10.1021/jp051025t.
8
Quantification of alpha-synuclein binding to lipid vesicles using fluorescence correlation spectroscopy.使用荧光相关光谱法对α-突触核蛋白与脂质囊泡的结合进行定量分析。
Biophys J. 2006 Jun 15;90(12):4692-700. doi: 10.1529/biophysj.105.079251. Epub 2006 Mar 31.
9
Specific anion effects on glass electrode pH measurements of buffer solutions: bulk and surface phenomena.
J Phys Chem B. 2006 Feb 16;110(6):2949-56. doi: 10.1021/jp0546296.
10
What makes the bioactive lipids phosphatidic acid and lysophosphatidic acid so special?具有生物活性的脂质磷脂酸和溶血磷脂酸为何如此特别？
Biochemistry. 2005 Dec 27;44(51):17007-15. doi: 10.1021/bi0518794.
Zotero 插件