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圈养肥尾沙鼠(Pachyuromys duprasi)的有效静脉穿刺技术及正常血清生化参数

An effective venipuncture technique and normal serum biochemistry parameters of the captive fat-tailed jird (Pachyuromys duprasi).

作者信息

Felt Stephen A, Guirguis Fady I, Wasfy Momtaz O, Howard Jim S, Domingo Neil V, Hussein Hussein I

机构信息

Animal Resources, Naval Medical Research Unit 3, Cairo, Egypt.

出版信息

J Am Assoc Lab Anim Sci. 2009 Jan;48(1):57-60.

PMID:19245752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2694701/
Abstract

Thirty-nine captively reared fat-tailed jirds (Pachyuromys duprasi) were enrolled in a minimally invasive study to determine an effective venipuncture technique and establish normal serum biochemistry parameters. A jugular venipuncture technique using chemical restraint (ketamine, 30 mg/kg; xylazine, 6 mg/kg; acepromazine, 1 mg/kg) administered intraperitoneally was safe and consistently yielded at least 0.3 mL of blood. Of the biochemical indicators measured (glucose, total protein, albumin, globulin, alkaline phosphatase, alanine transferase, total bilirubin, amylase, BUN, creatinine, calcium, phosphorous, sodium and potassium), amylase and glucose levels differed significantly between male and female fat-tailed jirds.

摘要

39只圈养繁殖的肥尾沙鼠(Pachyuromys duprasi)被纳入一项微创研究,以确定一种有效的静脉穿刺技术并建立正常的血清生化参数。使用腹腔注射化学保定剂(氯胺酮,30 mg/kg;赛拉嗪,6 mg/kg;乙酰丙嗪,1 mg/kg)的颈静脉穿刺技术是安全的,并且始终能采集到至少0.3 mL血液。在所测量的生化指标(葡萄糖、总蛋白、白蛋白、球蛋白、碱性磷酸酶、丙氨酸转氨酶、总胆红素、淀粉酶、尿素氮、肌酐、钙、磷、钠和钾)中,雄性和雌性肥尾沙鼠的淀粉酶和葡萄糖水平存在显著差异。

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本文引用的文献

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Lab Anim (NY). 2008 Jun;37(6):256-61. doi: 10.1038/laban0608-256.
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