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阻塞性睡眠呼吸暂停综合征作为工作能力丧失的预测因子。

Obstructive sleep apnoea syndrome as a predictor of work disability.

机构信息

Centre of Expertise for Work Organizations, Finnish Institute of Occupational Health, Lemminkäisenkatu 14-18B, FI-20520 Turku, Finland.

出版信息

Respir Med. 2009 Jul;103(7):1047-55. doi: 10.1016/j.rmed.2009.01.014. Epub 2009 Feb 26.

DOI:10.1016/j.rmed.2009.01.014
PMID:19246183
Abstract

STUDY OBJECTIVES

This study examined whether obstructive sleep apnoea syndrome (OSAS) is associated with increased risk of work disability during six years following the diagnosis.

DESIGN

Prospective follow-up study.

SETTING

Ten municipalities and six hospital districts in Finland.

PARTICIPANTS

A total of 766 employees with OSAS (cases), and their control subjects (n=3,827) matched for age, gender, socioeconomic position, type of employment contract and type of organization.

INTERVENTIONS

N/A.

MEASUREMENTS

Data on all (>9 days) or very long-term (>90 days) sickness absences and for disability pensions were obtained from national registers. Diagnosis of OSAS was determined according to the Hospital Discharge Register, which includes data on all hospital admissions.

RESULTS

According to the Cox proportional hazards models the hazard of the first sickness absence period (all sickness absences) during the follow-up was 1.7-fold (95% confidence interval (CI): 1.5-2.0) in male and 2.1-fold (95% CI: 1.8-2.4) in female sleep apnoea cases compared to controls after adjustments for sociodemographic factors. Both men and women with OSAS had a 2-fold increase in the risk for disability pension compared to controls. With regard to cause-specific work disability, employees with OSAS had a particularly pronounced risk of long-term work disability caused by injuries (HR 3.1 95% CI: 1.8-5.2) and mental disorders (HR: 2.8, CI 95%: 2.1-3.7).

CONCLUSIONS

These results suggest that OSAS is associated with an increased risk of both sickness absence and disability pension. They emphasize the need to identify the employees with this disorder and to improve general practitioners' knowledge about screening of sleep apnoea symptoms and indicators.

摘要

研究目的

本研究旨在探讨阻塞性睡眠呼吸暂停综合征(OSAS)与诊断后六年内工作残疾风险增加是否相关。

研究设计

前瞻性随访研究。

研究地点

芬兰十个市和六个医院区。

研究对象

共 766 名 OSAS 患者(病例)及其年龄、性别、社会经济地位、雇佣合同类型和组织类型相匹配的 3827 名对照者。

干预措施

无。

测量方法

所有(>9 天)或长期(>90 天)病假和残疾抚恤金的数据均从国家登记处获得。OSAS 的诊断依据是医院出院登记,其中包含所有住院患者的数据。

结果

根据 Cox 比例风险模型,在随访期间,男性 OSAS 病例首次病假(所有病假)的风险是对照组的 1.7 倍(95%可信区间(CI):1.5-2.0),女性是 2.1 倍(95% CI:1.8-2.4),校正社会人口因素后。与对照组相比,OSAS 男性和女性患残疾抚恤金的风险均增加了 2 倍。至于特定原因的工作残疾,OSAS 患者因受伤(HR 3.1,95% CI:1.8-5.2)和精神障碍(HR:2.8,95% CI:2.1-3.7)导致长期工作残疾的风险尤其显著。

结论

这些结果表明,OSAS 与病假和残疾抚恤金风险增加相关。它们强调了识别患有这种疾病的员工的必要性,并需要提高全科医生对睡眠呼吸暂停症状和指标筛查的认识。

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