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包括中子在内的高传能线密度辐射后较慢的细胞恢复，聚焦于DNA断裂的质量。

The slower cellular recovery after higher-LET irradiations, including neutrons, focuses on the quality of DNA breaks.

作者信息

Hendry J H

机构信息

Cancer Research Campaign Department of Radiation Biology, Paterson Institute for Cancer Research, Christie Hospital, Manchester, United Kingdom.

出版信息

Radiat Res. 1991 Oct;128(1 Suppl):S111-3.

PMID:1924735
Abstract

Data for many biological end points reviewed here indicate that the responsible lesions are not only more severe but also are often more slowly repaired as the LET of the ionizing radiation is increased. This is reflected in high RBE values for end points assayed at long (in contrast to short) times after irradiation, for example, residual injury in normal tissues and carcinogenesis.

摘要

此处回顾的许多生物学终点数据表明，随着电离辐射传能线密度（LET）的增加，相关损伤不仅更严重，而且修复往往更慢。这反映在辐照后长时间（与短时间相反）检测的终点的高相对生物效应（RBE）值上，例如正常组织中的残余损伤和致癌作用。

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