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血管内脑血运重建术后的高灌注综合征

Hyperperfusion syndrome following endovascular cerebral revascularization.

作者信息

Medel Ricky, Crowley R Webster, Dumont Aaron S

机构信息

Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA.

出版信息

Neurosurg Focus. 2009;26(3):E4. doi: 10.3171/2009.1.FOCUS08276.

Abstract

Endovascular cerebral revascularization is becoming a frequently used alternative to surgery for the treatment of atherosclerotic disease, especially in the intracranial circulation where options are limited. Recent literature regarding the equivalent efficacy of carotid artery stenting and carotid endarterectomy in certain patient populations, as well as the recognition of the significant risk for recurrent stroke posed by intracranial lesions, will only serve to amplify this trend. Hyperperfusion syndrome has been well documented in the setting of carotid endarterectomy; however, a paucity of literature exists regarding the incidence, pathophysiology, and management as it relates to percutaneous interventions. The purpose of this review is to outline the current state of knowledge, with particular attention to the distinct attributes of endovascular treatment that would be expected to modify the course of hyperperfusion syndrome.

摘要

血管内脑血运重建正成为治疗动脉粥样硬化疾病的一种常用手术替代方法,尤其是在颅内循环选择有限的情况下。近期有关在特定患者群体中颈动脉支架置入术和颈动脉内膜切除术等效疗效的文献,以及对颅内病变所致复发性卒中重大风险的认识,只会加剧这一趋势。高灌注综合征在颈动脉内膜切除术背景下已有充分记录;然而,关于其与经皮介入相关的发病率、病理生理学和管理的文献却很少。本综述的目的是概述当前的知识状况,尤其关注预期会改变高灌注综合征病程的血管内治疗的独特特性。

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