血液标本延迟处理后与临床化学和骨代谢相关分析物的稳定性。
Stability of analytes related to clinical chemistry and bone metabolism in blood specimens after delayed processing.
作者信息
Zwart Sara R, Wolf Megan, Rogers Ann, Rodgers Shanna, Gillman Patti L, Hitchcox Kristen, Ericson Karen L, Smith Scott M
机构信息
Universities Space Research Association, Houston, TX, USA.
出版信息
Clin Biochem. 2009 Jun;42(9):907-10. doi: 10.1016/j.clinbiochem.2009.02.010. Epub 2009 Feb 26.
OBJECTIVES
We investigated the stability of 36 analytes related to clinical chemistry in a controlled storage study.
DESIGN AND METHODS
Blood was collected from 11 subjects and was maintained for 45 min, 2.5 h, 5 h, or 24 h after phlebotomy before centrifugation.
RESULTS
Statistically significant changes were observed only for parathyroid hormone, osteocalcin, zinc, pyridoxal 5'-phosphate, and homocysteine.
CONCLUSIONS
These studies indicate that many analytes in clinical chemistry are stable for 24 h before centrifugation.
目的
在一项对照储存研究中，我们调查了36种与临床化学相关分析物的稳定性。
设计与方法
从11名受试者采集血液，在采血后离心前分别保存45分钟、2.5小时、5小时或24小时。
结果
仅观察到甲状旁腺激素、骨钙素、锌、5'-磷酸吡哆醛和同型半胱氨酸有统计学显著变化。
结论
这些研究表明，临床化学中的许多分析物在离心前24小时内是稳定的。
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