Potet F, Fléjou J F, Gervaz H, Paraf F
Service d'Anatomie et de Cytologie Pathologiques, Hôpital Bichat, Paris, France.
Semin Diagn Pathol. 1991 Aug;8(3):126-36.
This report describes adenocarcinoma in patients with Barrett's esophagus (BE) and adenocarcinoma of the esophagogastric junction (EGJ) and the gastric cardia. Definitions, frequency, and general features of both conditions are described. The macroscopic features and microscopic findings are detailed for invasive adenocarcinoma and superficial (early) adenocarcinoma. Prognosis and follow-up are evaluated using flow cytometry as a factor of prognosis. Precancerous conditions and etiological factors are discussed. In addition, primary adenocarcinoma of the lower esophagus not associated with BE is considered. The precancerous lesions and precancerous markers in BE and in the cardia are examined, including type of dysplasia, histochemical study, and other lines of research.
本报告描述了巴雷特食管（BE）患者以及食管胃交界（EGJ）和贲门腺癌患者的腺癌情况。阐述了这两种病症的定义、发病率及一般特征。详细介绍了浸润性腺癌和浅表（早期）腺癌的宏观特征及微观表现。将流式细胞术作为预后因素对预后和随访情况进行评估。探讨了癌前病症和病因。此外，还考虑了与BE无关的下食管原发性腺癌。对BE和贲门处的癌前病变及癌前标志物进行了研究，包括发育异常类型、组织化学研究及其他研究方向。
