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自行肌内注射双氯芬酸后皮肤坏死。

Skin necrosis after self-administered intramuscular diclofenac.

机构信息

Department of Orthopedics A, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, Tel-Aviv 64239, Israel.

出版信息

J Plast Reconstr Aesthet Surg. 2010 Jan;63(1):e4-5. doi: 10.1016/j.bjps.2009.01.049. Epub 2009 Feb 28.

DOI:10.1016/j.bjps.2009.01.049
PMID:19251506
Abstract

Intramuscular diclofenac is used extensively for pain relief in medical practice. Tissue necrosis is a rare but serious complication of intramuscular injections. The pathogenetic mechanism is still not completely understood. A case of tissue necrosis following self-administration of diclofenac inadvertently injected into an arterial perforator branch of the superficial femoral artery is reported, supporting a vascular pathogenesis.

摘要

肌肉内注射双氯芬酸在医学实践中被广泛用于缓解疼痛。组织坏死是肌肉内注射的一种罕见但严重的并发症。其发病机制尚不完全清楚。报告了一例自行注射双氯芬酸时意外注射到股浅动脉穿支动脉的组织坏死病例,支持血管发病机制。

相似文献

1
Skin necrosis after self-administered intramuscular diclofenac.自行肌内注射双氯芬酸后皮肤坏死。
J Plast Reconstr Aesthet Surg. 2010 Jan;63(1):e4-5. doi: 10.1016/j.bjps.2009.01.049. Epub 2009 Feb 28.
2
Nicolau syndrome following intramuscular diclofenac injection: a case report.肌肉注射双氯芬酸后发生的尼科劳综合征:一例报告
Dermatol Ther. 2008 Jul;21 Suppl 1:S10-2. doi: 10.1111/j.1529-8019.2008.00195.x.
3
Nicolau syndrome after diclofenac injection.双氯芬酸注射后出现尼科劳综合征。
J Eur Acad Dermatol Venereol. 2007 Feb;21(2):266-7. doi: 10.1111/j.1468-3083.2006.01837.x.
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Nicolau syndrome and perforator vessels: a new viewpoint for an old problem.尼科劳综合征与穿支血管:一个老问题的新视角
Cutan Ocul Toxicol. 2010 Mar;29(1):70-2. doi: 10.3109/15569520903496753.
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Nicolau syndrome: a report of 2 cases.尼科劳综合征:2例报告。
J Drugs Dermatol. 2006 Apr;5(4):377-8.
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Nicolau syndrome aggravated by cold application after i.m. diclofenac.肌内注射双氯芬酸后冷敷加重尼科劳综合征。
J Dermatol. 2008 Jan;35(1):18-20. doi: 10.1111/j.1346-8138.2007.00404.x.
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Nicolau syndrome in an athlete following intra-muscular diclofenac injection.一名运动员肌肉注射双氯芬酸后发生尼科劳综合征。
Acta Orthop Belg. 2008 Dec;74(6):860-4.
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[Intramuscular application of diclofenac--case report and critical consideration of a therapeutic measure].双氯芬酸的肌肉注射应用——病例报告及对一种治疗措施的批判性思考
Z Orthop Ihre Grenzgeb. 2004 Jul-Aug;142(4):489-92. doi: 10.1055/s-2004-820313.
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[Intramuscular injections of diclofenac].[双氯芬酸肌肉注射]
Dtsch Med Wochenschr. 1997 Sep 26;122(39):1195-6.
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Multiple diclofenac-induced adverse effects.双氯芬酸引起的多种不良反应。
Am J Gastroenterol. 2000 Oct;95(10):2988-9. doi: 10.1111/j.1572-0241.2000.03218.x.

引用本文的文献

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Nicolau Syndrome: An Unforeseen Yet Evadable Consequence of Intramuscular Injection.尼科劳综合征:肌肉注射一种意想不到但可避免的后果。
Surg J (N Y). 2021 May 25;7(2):e62-e65. doi: 10.1055/s-0041-1728652. eCollection 2021 Apr.
2
Nicolau Syndrome due to Penicillin Injection: A Report of 3 Cases without Long-Term Complication.青霉素注射所致尼科劳综合征:3例无长期并发症报告
Case Rep Infect Dis. 2016;2016:9082158. doi: 10.1155/2016/9082158. Epub 2016 Nov 1.
3
Freestyle Perforator-Based Fasciocutaneous Flap Reconstruction in Nicolau Syndrome-Related Tissue Necrosis.
基于游离穿支皮瓣的筋膜皮瓣重建术治疗尼科劳综合征相关组织坏死
Indian J Surg. 2015 Dec;77(Suppl 3):1187-90. doi: 10.1007/s12262-015-1239-2. Epub 2015 Feb 8.
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Nicolau syndrome due to diclofenac sodium (Voltaren®) injection: a case report.双氯芬酸钠(扶他林®)注射导致的尼科劳综合征:一例报告。
J Med Case Rep. 2014 Dec 4;8:404. doi: 10.1186/1752-1947-8-404.