Department of Orthopedics A, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, Tel-Aviv 64239, Israel.
J Plast Reconstr Aesthet Surg. 2010 Jan;63(1):e4-5. doi: 10.1016/j.bjps.2009.01.049. Epub 2009 Feb 28.
Intramuscular diclofenac is used extensively for pain relief in medical practice. Tissue necrosis is a rare but serious complication of intramuscular injections. The pathogenetic mechanism is still not completely understood. A case of tissue necrosis following self-administration of diclofenac inadvertently injected into an arterial perforator branch of the superficial femoral artery is reported, supporting a vascular pathogenesis.
肌肉内注射双氯芬酸在医学实践中被广泛用于缓解疼痛。组织坏死是肌肉内注射的一种罕见但严重的并发症。其发病机制尚不完全清楚。报告了一例自行注射双氯芬酸时意外注射到股浅动脉穿支动脉的组织坏死病例,支持血管发病机制。