Panariello Luigia, Ayala Fabio
Department of Dermatology, University of Naples Federico II, Naples, Italy.
Dermatol Ther. 2008 Jul;21 Suppl 1:S10-2. doi: 10.1111/j.1529-8019.2008.00195.x.
Nicolau syndrome (NS) is a rare complication of intramuscular injection of various drugs which clinically presents with extensive necrosis of skin, subcutaneous and even muscle tissue. We describe a case of NS following intramuscular injection of diclofenac.
尼科劳综合征（NS）是肌肉注射各种药物后罕见的并发症，临床上表现为皮肤、皮下甚至肌肉组织的广泛坏死。我们描述了一例肌肉注射双氯芬酸后发生尼科劳综合征的病例。
