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解读“心力衰竭流行趋势”:对心力衰竭决定因素趋势的系统评价

Understanding the 'epidemic of heart failure': a systematic review of trends in determinants of heart failure.

作者信息

Najafi Farid, Jamrozik Konrad, Dobson Annette J

机构信息

Kermanshah Health Research Center (KHRC), Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

Eur J Heart Fail. 2009 May;11(5):472-9. doi: 10.1093/eurjhf/hfp029. Epub 2009 Feb 27.

DOI:10.1093/eurjhf/hfp029
PMID:19251729
Abstract

AIMS

We conducted a systematic review of recent studies investigating trends in the epidemiology of heart failure (HF).

METHODS AND RESULTS

We fitted simple linear regression models of rates against calendar year for mortality and hospital admission. Based on Population Attributable Fractions (PAFs) from the NHANES I Epidemiological Follow-up Study and self-reported prevalences of risk factors for HF, the estimated changes in numbers of new cases of HF in Australia were calculated from 1995 to 2005. A clear decline in mortality from HF and some data on decreases in admissions to hospitals for HF, as well as the lack of reports showing an increase in the incidence of HF, all argue against the existence of an 'epidemic' of HF. However, most reports on trends in HF survival have shown a secular improvement. The latter, together with population aging, are major factors that may increase the caseload of HF. Against this background of conflicting influences, we estimate that in Australia, the inflow into the caseload of HF decreased by 1.6% among people aged > or =55 years in 2005 relative to 1995.

CONCLUSION

Available evidence does not support an increase in the caseload of HF over recent years. Taking all of the influences on the epidemiology of HF together, it is likely that the number of new cases of HF will rise over the next few years, even if the incidence rate falls, chiefly because the elderly population is expanding so quickly.

摘要

目的

我们对近期有关心力衰竭(HF)流行病学趋势的研究进行了系统综述。

方法与结果

我们针对死亡率和住院率拟合了随日历年变化的简单线性回归模型。根据美国国家健康和营养检查调查(NHANES)I流行病学随访研究中的人群归因分数(PAFs)以及HF危险因素的自我报告患病率,计算了1995年至2005年澳大利亚HF新发病例数的估计变化。HF死亡率明显下降,有一些关于HF住院人数减少的数据,而且没有报告显示HF发病率增加,所有这些都表明不存在HF“流行”。然而,大多数关于HF生存率趋势的报告显示长期有所改善。后者与人口老龄化一起,是可能增加HF病例数的主要因素。在这种相互矛盾的影响背景下,我们估计在澳大利亚,2005年相对于1995年,年龄≥55岁人群中进入HF病例数队列的人数减少了1.6%。

结论

现有证据不支持近年来HF病例数增加。综合考虑所有对HF流行病学的影响,即使发病率下降,未来几年HF新发病例数也可能上升,主要是因为老年人口增长迅速。

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