Khan Afsar, Ahmad Viqar Uddin, Farooq Umar, Bader Sadia, Arshad Saima
H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan.
Chem Pharm Bull (Tokyo). 2009 Mar;57(3):276-9. doi: 10.1248/cpb.57.276.
A BuOH-soluble part of the methanolic extract from the roots of Otostegia limbata yielded two new flavonol glycosides; kaempferol 3-O-[beta-D-glucopyranosyl-(1-->2)-[beta-D-glucopyranosyl-(1-->3)]-[beta-D-glucopyranosyl-(1-->4)]-alpha-L-rhamnopyranoside]-7-O-[alpha-L-rhamnopyranoside] (1) and kaempferol 3-O-[beta-D-glucopyranosyl-(1-->4)-beta-D-6'''''[4-hydroxy (E)-cinnamoyl]glucopyranosyl-(1-->3)-[beta-D-glucopyranosyl-(1-->2)]-alpha-L-rhamnopyranoside]-7-O-[alpha-L-rhamnopyranoside] (2). The structures of these compounds were elucidated by spectroscopic and chemical means. To the best of our knowledge, these are the largest flavonoids derivatives described so far from the genus Otostegia.
从具缘耳草根部甲醇提取物的正丁醇可溶部分中得到了两种新的黄酮醇苷；山柰酚3 - O - [β - D - 吡喃葡萄糖基 - (1→2) - [β - D - 吡喃葡萄糖基 - (1→3)] - [β - D - 吡喃葡萄糖基 - (1→4)] - α - L - 鼠李吡喃糖苷] - 7 - O - [α - L - 鼠李吡喃糖苷]（1）和山柰酚3 - O - [β - D - 吡喃葡萄糖基 - (1→4) - β - D - 6''''[4 - 羟基（E） - 肉桂酰基]吡喃葡萄糖基 - (1→3) - [β - D - 吡喃葡萄糖基 - (1→2)] - α - L - 鼠李吡喃糖苷] - 7 - O - [α - L - 鼠李吡喃糖苷]（2）。这些化合物的结构通过光谱和化学方法得以阐明。据我们所知，这些是迄今为止从耳草属中描述的最大的黄酮类衍生物。
