Larsen Erling, Blaakaer Jan
Department of Gynecology and Obstetrics, Aarhus University Hospital, Denmark.
Acta Obstet Gynecol Scand. 2009;88(4):373-7. doi: 10.1080/00016340902814559.
Worldwide, much effort is used every day to perform optimal surgery in the treatment of epithelial ovarian cancer. Treatment of ovarian cancer is a combination of surgery with optimal debulking followed by chemotherapy. However, the optimal timing of postoperative chemotherapy for ovarian cancer remains poorly defined. The literature is made up of seven studies performed in different ways and which have included varying prognostic factors. The general supposition is that the time interval (TI) does not have a prognostic influence but experimental studies have shown that it does affect the prognosis of the cancer. This commentary focuses on the importance of the TI between surgery and postoperative chemotherapy in this horrible disease.
在全球范围内，每天都投入大量精力为上皮性卵巢癌患者实施最佳手术治疗。卵巢癌的治疗是手术与最佳肿瘤细胞减灭术相结合，随后进行化疗。然而，卵巢癌术后化疗的最佳时机仍不明确。相关文献由七项采用不同方法开展的研究组成，这些研究纳入了各不相同的预后因素。一般的推测是时间间隔（TI）没有预后影响，但实验研究表明它确实会影响癌症的预后。本述评聚焦于在这种可怕疾病中手术与术后化疗之间时间间隔的重要性。
