Manandhar A, Paudel G, Rai C K, Rai S K, Gurung R, Ruit S
Tilganga Eye Center, Gausala, Nepal.
Nepal Med Coll J. 2008 Sep;10(3):196-8.
Seasonal hyperacute panuveitis (SHAPU), characterized by an unusual form of unilateral severe hyper acute diffused intraocular inflammation, is one of the mysterious eye diseases of which the definite cause and treatment remains yet to be tound out. In this study, a total of six cases were included. Aqueous and vitreous samples were subjected to direct microscopy and culture (bacterial or fungal). Of the six cases included, two yielded Streptococcus pneumoniae and one Acinetobactor sp. on culture. All three culture positive samples showed pus cells in direct microscopic examination (gram stain). All cases were subjected to vitrectomy and intravitreal antibiotic and steroid injection, along with oral antibiotics and steroid. Five cases were also treated with antiviral agent. After treatment four cases showed reversal of hypotony and three cases recovered some vision.
季节性超急性全葡萄膜炎（SHAPU），其特征为一种不寻常的单侧严重超急性弥漫性眼内炎症形式，是病因和治疗方法仍有待明确的神秘眼病之一。本研究共纳入6例病例。对房水和玻璃体样本进行直接显微镜检查和培养（细菌或真菌）。在纳入的6例病例中，2例培养出肺炎链球菌，1例培养出不动杆菌属。所有3份培养阳性样本在直接显微镜检查（革兰氏染色）中均显示有脓细胞。所有病例均接受了玻璃体切除术、玻璃体内抗生素和类固醇注射，以及口服抗生素和类固醇。5例还接受了抗病毒药物治疗。治疗后，4例低眼压情况得到逆转，3例恢复了部分视力。
