Upadhyay M P, Rai N C, Ogg J E, Shrestha B R
Ann Ophthalmol. 1984 Jan;16(1):38-44.
A severe form of unilateral uveitis, which in most cases leads to blindness within hours of its onset, has been seen in Nepal since 1975. This disease appears with the onset of autumn in early September and lasts until the end of December in two-year cycles (1975, 1977, 1979). However, some cases occurred in 1980 as well. As expected there was an outbreak of this disease in 1981. Although early cases were seen in patients from Western Nepal, the disease has since been identified in patients from various parts of the country. In one of the outbreaks (1977) in western Nepal some patients or their parents gave a history of a white moth sitting on the child's face or arm prior to the onset of ocular symptoms. Some of these were claimed to be followed by blister formation at the point of contact. These moths were presumed to be responsible for producing this uveitis in those cases. The present report describes the clinical features of the cases seen from the time the disease was first recognized, case histories of four cases seen during the last outbreak, results of laboratory experiments using the aqueous humor of these patients, and the results of experiments using three different varieties of moths.
自1975年以来，尼泊尔出现了一种严重的单眼葡萄膜炎，多数情况下在发病数小时内即可导致失明。这种疾病于9月初秋季开始时出现，以两年为周期持续到12月底（1975年、1977年、1979年）。不过，1980年也出现了一些病例。不出所料，1981年该病爆发。虽然最初在尼泊尔西部的患者中发现了病例，但此后在该国各地的患者中都发现了这种疾病。在尼泊尔西部的一次疫情（1977年）中，一些患者或其父母称，在眼部症状出现之前，有一只白色蛾子落在孩子的脸上或手臂上。其中一些人声称接触部位随后出现了水泡。据推测，这些蛾子是导致这些病例发生葡萄膜炎的原因。本报告描述了自首次发现该疾病以来所见到病例的临床特征、上次疫情期间所见4例的病例史、使用这些患者房水进行的实验室实验结果以及使用三种不同种类蛾子进行的实验结果。
