Cunningham Arquita S, Muneyyirci-Delale Ozgul
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, SUNY Downstate Medical Center, 450 Clarkson Ave, Box 24, Brooklyn, NY 11203, USA.
Med Hypotheses. 2009 Jul;73(1):90-1. doi: 10.1016/j.mehy.2008.12.048. Epub 2009 Feb 28.
Primary dysmenorrhea (PD) and hyperemesis gravidarum (HG) are two diseases that the overall etiologies are both unknown. There are several contributing factors that lead to both PD and HG. We chose to focus on an increase in prostaglandin and hormone levels due to an observation of several patients with HG that reported PD after menarche. After review of several studies, we hypothesize that there is a positive correlation between PD and HG. Further, larger studies will be needed to make a more accurate assessment in the connection of patients with PD being more prone to HG in their first pregnancy as well as subsequent pregnancies.
原发性痛经（PD）和妊娠剧吐（HG）是两种病因尚不明确的疾病。有几个共同因素会导致PD和HG。由于观察到几名患有HG的患者在初潮后出现了PD，我们选择重点关注前列腺素和激素水平的升高。在查阅了几项研究后，我们推测PD和HG之间存在正相关。此外，需要进行更大规模的研究，以便更准确地评估患有PD的患者在首次怀孕及后续怀孕中更容易患HG之间的联系。
