Li Yubin, Dooner Hugo K
Department of Plant Biology, Rutgers University, New Brunswick, New Jersey 08901, USA.
Genetics. 2009 May;182(1):399-402. doi: 10.1534/genetics.109.101527. Epub 2009 Mar 2.
Helitrons are novel transposons discovered by bioinformatic analysis of eukaryotic genome sequences. They are believed to move by rolling circle (RC) replication because their predicted transposases are homologous to those of bacterial RC transposons. We report here evidence of somatic Helitron excision in maize, an unexpected finding suggesting that Helitrons can exhibit an excisive mode of transposition.
Helitron转座子是通过对真核生物基因组序列进行生物信息学分析发现的新型转座子。它们被认为通过滚环(RC)复制进行移动,因为其预测的转座酶与细菌RC转座子的转座酶同源。我们在此报告玉米中体细胞Helitron切除的证据,这一意外发现表明Helitron转座子可呈现一种切除式转座模式。