Australian Technology Network Centre for Metabolic Fitness, Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia.
Int J Obes (Lond). 2009 Apr;33(4):387-400. doi: 10.1038/ijo.2009.42. Epub 2009 Mar 3.
This review addresses the effect of overweight and obese weight status on pediatric health-related quality of life (HRQOL).
Web of Science, Medline, CINAHL, Cochrane Library, EMBASE, AMED and PubMed were searched for peer-reviewed studies in English reporting HRQOL and weight status in youth (<21 years), published before March 2008.
Twenty-eight articles were identified. Regression of HRQOL against body mass index (BMI) using pooled data from 13 studies utilizing the Pediatric Quality of Life Inventory identified an inverse relationship between BMI and pediatric HRQOL (r=-0.7, P=0.008), with impairments in physical and social functioning consistently reported. HRQOL seemed to improve with weight loss, but randomized controlled trials were few and lacked long-term follow-up.
Little is known about the factors associated with reduced HRQOL among overweight or obese youth, although gender, age and obesity-related co-morbidities may play a role. Few studies have examined the differences in HRQOL between community and treatment-seeking samples. Pooled regressions suggest pediatric self-reported HRQOL can be predicted from parent proxy reports, although parents of obese youths tend to perceive worse HRQOL than children do about themselves. Thus, future research should include both pediatric and parent proxy perspectives.
本综述旨在探讨超重和肥胖对儿童健康相关生活质量（HRQOL）的影响。
检索了 Web of Science、Medline、CINAHL、Cochrane Library、EMBASE、AMED 和 PubMed 数据库，以获取截至 2008 年 3 月前发表的有关儿童（<21 岁）体重状况与 HRQOL 的同行评议英文文献。
共确定了 28 篇文章。利用利用儿科生活质量量表对 13 项研究的数据进行的回归分析显示，HRQOL 与体重指数（BMI）呈负相关（r=-0.7，P=0.008），身体和社会功能受损的情况较为常见。HRQOL 似乎随着体重的减轻而改善，但随机对照试验较少，缺乏长期随访。
尽管性别、年龄和肥胖相关合并症可能发挥作用，但目前尚不清楚超重或肥胖儿童中哪些因素与 HRQOL 降低有关。很少有研究探讨社区和寻求治疗的样本之间 HRQOL 的差异。综合回归分析表明，儿童自我报告的 HRQOL 可以从家长代理报告中预测，尽管肥胖儿童的家长往往对儿童的 HRQOL 评价比儿童自己更差。因此，未来的研究应同时包含儿童和家长的观点。
