Hughes A R, Farewell K, Harris D, Reilly J J
Division of Developmental Medicine, Yorkhill Hospitals, University of Glasgow, Glasgow, UK.
Int J Obes (Lond). 2007 Jan;31(1):39-44. doi: 10.1038/sj.ijo.0803410. Epub 2006 May 30.
To measure health-related quality of life (HRQoL) in a clinical sample of obese children by child self-report and parent-proxy report; to compare quality of life assessments provided by obese children and their parents; to assess differences in quality of life between the obese clinical sample and healthy control children.
Pairwise comparison of obese children matched for age, gender and socio-economic status with non-obese controls.
One hundred and twenty-six obese children (body mass index (BMI) >/=98th centile) and 71 lean control children (BMI <85th centile). Controls were matched with 71 children from the obese clinical group (mean age 8.6, standard deviation (s.d.) 1.9 years; 33 M/38 F).
The Paediatric Quality of Life Inventory (UK) version 4 was self-administered to parents and to children aged 8-12 years and interview was administered to children aged 5-7 years. This questionnaire assessed physical, social, emotional and school functioning from which total, physical and psychosocial health summary scores were derived.
In the obese clinical group (n=126), parent proxy-reported quality of life was low for all domains. In the obese clinical group, parent-reported scores were significantly lower than child self-reported scores in all domains except physical health and school functioning. Parent-proxy reports were significantly higher for healthy controls than obese children in all domains (median total score 85.2 vs 64.7; 95% confidence interval (CI) 15.6, 24.1). For child self-reports, only physical health was significantly higher for healthy controls than obese children (median score 81.3 vs 75.0; 95% CI 3.1, 12.5).
HRQoL is impaired in clinical samples of obese children compared to lean children, but the degree of impairment is likely to be greatest when assessed using the parent perspective rather than the child perspective.
通过儿童自我报告和家长代理报告来测量肥胖儿童临床样本中的健康相关生活质量（HRQoL）；比较肥胖儿童及其家长提供的生活质量评估；评估肥胖临床样本与健康对照儿童之间的生活质量差异。
将年龄、性别和社会经济地位相匹配的肥胖儿童与非肥胖对照进行成对比较。
126名肥胖儿童（体重指数（BMI）≥第98百分位数）和71名瘦对照儿童（BMI＜第85百分位数）。对照与肥胖临床组的71名儿童相匹配（平均年龄8.6岁，标准差（s.d.）1.9岁；33名男性/38名女性）。
《儿童生活质量量表（英国）》第4版由家长自行填写，8至12岁儿童自行填写，5至7岁儿童通过访谈填写。该问卷评估了身体、社交、情感和学校功能，并由此得出总体、身体和心理社会健康汇总分数。
在肥胖临床组（n = 126）中，家长代理报告的所有领域生活质量均较低。在肥胖临床组中，除身体健康和学校功能外，家长报告的所有领域分数均显著低于儿童自我报告的分数。在所有领域，健康对照儿童的家长代理报告分数均显著高于肥胖儿童（总分数中位数85.2对64.7；95%置信区间（CI）15.6，24.1）。对于儿童自我报告，只有健康对照儿童的身体健康显著高于肥胖儿童（分数中位数81.3对75.0；95% CI 3.1，12.5）。
与瘦儿童相比，肥胖儿童临床样本中的HRQoL受损，但从家长角度而非儿童角度评估时，受损程度可能最大。
