Roldán-Marín Rodrigo, de la Barreda-Becerril Fernando, Toussaint-Caire Sonia, Piñeiro-Acosta Eduardo
División de Consulta Externa, Hospital General Dr. Manuel Gea González, México D. F., México.
Gac Med Mex. 2009 Jan-Feb;145(1):61-4.
Transepidermal elimination is a mechanism by which altered dermal extracellular material is discharged through the epidermis. Perforating elastosis is a rare disease characterized by the transepidermal elimination of abnormal elastic fibers. Clinically it manifests as skin-colored keratotic papules that may coalesce and form arcuate or serpiginous plaques. It affects mostly males, predominantly younger than 30-years-old. We present a case of a male patient with inflammatory bowel disease and sclerosing cholangitis associated with perforating elastosis. To our knowledge, this is the first description of inflammatory bowel disease associated with perforating elastosis.
经表皮消除是一种机制，通过该机制，改变的真皮细胞外物质通过表皮排出。穿通性弹力纤维变性是一种罕见疾病，其特征是异常弹性纤维经表皮消除。临床上表现为肤色角化丘疹，可融合并形成弓形或匐行性斑块。它主要影响男性，主要是30岁以下的男性。我们报告一例患有炎症性肠病和硬化性胆管炎并伴有穿通性弹力纤维变性的男性患者。据我们所知，这是首次描述炎症性肠病与穿通性弹力纤维变性相关。
