Shub Denis, Darvishi Roham, Kunik Mark E
Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, USA.
Geriatrics. 2009 Feb;64(2):22-6.
The prevalence of insomnia increases with age and affects up to 35% of community-dwelling adults with dementia. Sleep disturbances and associated cognitive and behavioral symptoms in this patient population can be a significant contributor to morbidity, mortality, and caregiver burden. Despite the frequency with which sleep disorders are encountered in primary care, few evidence-based guidelines are available to guide physician treatment plans. Sedative-hypnotic medications are commonly prescribed but are associated with significant adverse effects and have limited efficacy data. Non-pharmacologic treatments can be safe and effective adjuncts or alternatives to medications but are often underused in clinical practice. This article reviews practical applications of modalities such as light therapy, exercise, and sleep-hygiene modification in treating insomnia in persons with dementia.
失眠的患病率随年龄增长而增加,影响高达35%的社区痴呆成年人。该患者群体的睡眠障碍以及相关的认知和行为症状可能是发病率、死亡率和护理负担的重要因素。尽管在初级保健中睡眠障碍很常见,但几乎没有基于证据的指南可指导医生的治疗方案。镇静催眠药物是常用的处方药,但会产生显著的副作用,且疗效数据有限。非药物治疗可以是安全有效的药物辅助手段或替代方法,但在临床实践中往往未得到充分利用。本文综述了光疗、运动和改善睡眠卫生等方法在治疗痴呆症患者失眠方面的实际应用。