OCT4B1亚型：作为一种假定的干性标志物的新型OCT4可变剪接变体。
OCT4B1 isoform: the novel OCT4 alternative spliced variant as a putative marker of stemness.
作者信息
Papamichos Spyros I, Kotoula Vassiliki, Tarlatzis Basil C, Agorastos Theodoros, Papazisis Konstantinos, Lambropoulos Alexandros F
机构信息
First Department of Obstetrics and Gynaecology, General Regional Hospital Papageorgiou, Aristotle University, Thessaloniki, Greece.
出版信息
Mol Hum Reprod. 2009 May;15(5):269-70. doi: 10.1093/molehr/gap018. Epub 2009 Mar 3.
A novel OCT4 alternative spliced variant (OCT 4B1) is deduced to be the isoform present in 59 hESC lines characterised by the International Stem Cell Initiative (ISCI) rather than OCT4A as previously assumed. The new variant may be a more reliable marker of stemness than OCT4A and studies are needed to test this.
一种新的OCT4可变剪接变体（OCT 4B1）被推断为国际干细胞倡议组织（ISCI）所鉴定的59个人类胚胎干细胞系中存在的异构体，而非先前认为的OCT4A。与OCT4A相比，这种新变体可能是一种更可靠的干性标志物，需要开展研究来对此进行验证。
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