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一名绝经前女性经手术治疗后经组织病理学诊断为大卵巢卵泡膜细胞瘤的罕见病例:病例报告及当前文献综述

A Rare Case of Large Ovarian Thecoma Diagnosed Histopathologically Following Surgical Management in a Premenopausal Woman: A Case Report and Review of the Current Literature.

作者信息

Lugata John, Makower Laetitia, Rapheal Ashley, Kaleshu Julius, Lyamuya Tecla, Mchome Bariki, Mremi Alex

机构信息

Department of Obstetrics and Gynecology Kilimanjaro Christian Medical Centre Moshi Tanzania.

Faculty of Medicine Kilimanjaro Christian Medical University College Moshi Tanzania.

出版信息

Clin Case Rep. 2025 May 23;13(5):e70528. doi: 10.1002/ccr3.70528. eCollection 2025 May.

Abstract

Ovarian thecomas are rare sex cord-stromal tumors of the ovary. These tumors are estimated to account for 1% of all ovarian neoplasms. Thecomas are primarily composed of cells that resemble theca cells, which are involved in estrogen production. While thecomas are more frequently observed in postmenopausal women, they can also occur in premenopausal women. This report presents a rare case of an ovarian thecoma in a premenopausal woman and reviews the current literature on the topic. Herein we endeavor to contribute to the current body of knowledge and provide guidance to clinicians managing similar cases. Our patient is 43 years old and was diagnosed with an ovarian thecoma after she presented to our facility complaining of abdominal pain and abdominal distension. She underwent a total abdominal hysterectomy and unilateral salpingo-oophorectomy. Histopathological examination confirmed a benign thecoma. We demonstrate that it is crucial to consider this benign condition when evaluating solid ovarian tumors in premenopausal women.

摘要

卵巢卵泡膜细胞瘤是一种罕见的卵巢性索间质肿瘤。据估计,这些肿瘤占所有卵巢肿瘤的1%。卵泡膜细胞瘤主要由类似于卵泡膜细胞的细胞组成,这些细胞参与雌激素的产生。虽然卵泡膜细胞瘤在绝经后女性中更常见,但也可发生于绝经前女性。本报告介绍了一例绝经前女性卵巢卵泡膜细胞瘤的罕见病例,并回顾了关于该主题的当前文献。在此,我们努力为当前的知识体系做出贡献,并为处理类似病例的临床医生提供指导。我们的患者43岁,因腹痛和腹胀前来我院就诊,被诊断为卵巢卵泡膜细胞瘤。她接受了全腹子宫切除术和单侧输卵管卵巢切除术。组织病理学检查证实为良性卵泡膜细胞瘤。我们证明,在评估绝经前女性的实性卵巢肿瘤时,考虑这种良性疾病至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7a/12100755/c5b5e730fe02/CCR3-13-e70528-g002.jpg

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