Zwart P
Hoogleraar in de Ziektekunde van Laboratorium- en van Bijzondere Dieren, Utrecht.
Tijdschr Diergeneeskd. 1991 Aug 15;116(15-16):781-8.
Normal and abnormal situations in the reptilian ovary are reviewed. The normal development of the ovary is mainly governed by the temperature and variations in length of daylight. Vitellogenesis, (the production of yolk) takes place in the liver and is regulated by oestrogens. Under an abnormal light regimen, for instance 12 hours of light--12 hours of darkness, erratic vitellogenesis may occur. Atresia or resorption of follicles may occur at all stages of their development. The pathology of the process of resorption is characterised by the invasion of blood vessels and phagocytosis of yolk by macrophages. Pseudopregnancy is referred to for the first time. An important pathological aspect is the sterile inflammation of the ovary, which is fairly common in reptiles. The pathogenesis most probably is a trauma or some other defect of the egg membrane, resulting in leakage of vitelline into the surrounding fatty tissues. This contact gives rise to a chronic granulomatous inflammation. Comparative pathology covers a very wide field. In the Department of Special Animal Pathology, the specialization known in other areas of the veterinary profession, is directed towards a concentration of staff members on certain groups of animals such as mammals, birds, reptiles and laboratory animals respectively. At thesis was advanced, stating that a problem-solving attitude of the students cannot be solely attained by participation of veterinary students in fundamental research. The department of veterinary pathology is devoted to a problem-solving mode of education of students.