Nouws J F, Verdijk A T
RVV-Kring 6, Nijmegen.
Tijdschr Diergeneeskd. 1991 Sep 1;116(17):833-40.
The causes of the presence of antibiotic residues in slaughtered animals are analysed. The fact is stressed that the persistence of antibiotic residues in slaughtered animals varies, among other things, with the antibiotic itself, the pharmaceutical design and, in the case of subcutaneous or intramuscular injection, the site of injection and the severity of local irritation of the tissues. There are marked differences between the various antibiotic products as regards the local irritation induced and the residual persistence in organs at the site of injection. A selective use of antibiotics and forms of administration (so-called 'positive list') is advocated, by which the incidence of antibiotic residues in slaughtered animals can be restricted. Recommendations for drawing up a 'positive' list' are made.
分析了屠宰动物中存在抗生素残留的原因。着重指出，屠宰动物中抗生素残留的持续性存在差异，除其他因素外，这与抗生素本身、药物设计有关，对于皮下或肌肉注射而言，还与注射部位以及组织局部刺激的严重程度有关。不同抗生素产品在注射部位引起的局部刺激以及在器官中的残留持续性方面存在显著差异。提倡选择性使用抗生素及其给药形式（所谓的“阳性清单”），通过这种方式可以限制屠宰动物中抗生素残留的发生率。还提出了制定“阳性清单”的建议。
