Köhler H
Kinder- und Jugendklinik, Universitätsklinikum Erlangen.
Klin Padiatr. 2009 Mar-Apr;221(2):54-6. doi: 10.1055/s-0029-1192009. Epub 2009 Mar 4.
In Germany Salmonella belong to the most frequently detected pathogens in bacterial enteritis, Remarkably infants show a higher incidence than adults. In addition to the intestinal symptoms extraintestinal complications, such as bacteremia, infections of the central nervous system and osteomyelitis, are responsible for the disease severity. An age specific source of infection is the often hardly detectable contamination of powdered infant formula. Also infants seem very susceptible to disease transmission through reptiles held in the family's home. Immunologic functions, which are partly age dependent, might be responsible for a high susceptibility and severe salmonella infection in individuals. Due to the reported problems infected infants under 6 months should receive antibiotic therapy. The use of probiotics is not (yet) established in this setting.
在德国,沙门氏菌是细菌性肠炎中最常检测到的病原体之一。值得注意的是,婴儿的发病率高于成人。除肠道症状外,菌血症、中枢神经系统感染和骨髓炎等肠外并发症也是导致病情严重的原因。特定年龄段的感染源通常是难以检测到的婴儿配方奶粉污染。此外,婴儿似乎极易通过家中饲养的爬行动物感染疾病。部分依赖年龄的免疫功能可能是个体易感性高和沙门氏菌感染严重的原因。鉴于所报告的问题,6个月以下的感染婴儿应接受抗生素治疗。在这种情况下,益生菌的使用尚未得到证实。