Nandagopal Jayasree J, DelBello Melissa P, Kowatch Robert
Department of Psychiatry, University of Cincinnati, College of Medicine, 260 Stetson Street, Cincinnati, OH 45267, USA.
Child Adolesc Psychiatr Clin N Am. 2009 Apr;18(2):455-69, x. doi: 10.1016/j.chc.2008.11.004.
Bipolar disorder (BPD) is being diagnosed with increasing frequency in the pediatric population as the phenomenology of this disorder is becoming more clearly delineated. Early diagnosis and treatment of pediatric BPD is important to minimize psychosocial disability and improve prognosis. Traditional mood stabilizers and atypical antipsychotic agents are frequently used to treat BPD in youth, and there are emerging data to support their use in this population. This article provides a review of the literature on appropriate pharmacologic treatment strategies for BPD in children and adolescents. The complex treatment issues of comorbid BPD and attention deficit/hyperactivity disorder also are addressed.
随着双相情感障碍（BPD）的症状表现日益清晰，该疾病在儿科人群中的诊断频率不断增加。早期诊断和治疗小儿双相情感障碍对于将心理社会残疾降至最低并改善预后至关重要。传统心境稳定剂和非典型抗精神病药物常用于治疗青少年双相情感障碍，并且有新的数据支持它们在该人群中的应用。本文综述了关于儿童和青少年双相情感障碍适当药物治疗策略的文献。还讨论了双相情感障碍与注意力缺陷/多动障碍共病的复杂治疗问题。
