Morden Nancy E, Mistler Lisa A, Weeks William B, Bartels Stephen J
Department of Community and Family Medicine, Dartmouth Medical School, The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH, USA.
J Am Board Fam Med. 2009 Mar-Apr;22(2):187-95. doi: 10.3122/jabfm.2009.02.080059.
Numerous studies document disproportionate physical morbidity and premature death among people with serious mental illness. Although suicide remains an important cause of mortality for this population, cardiovascular disease is the leading cause of death. Cardiovascular death among those with serious mental illness is 2 to 3 times that of the general population. This vulnerability is commonly attributed to underlying mental illness and behavior. Some excess disease and deaths result from poor access to and use of quality health care. Negative cardiometabolic effects of newer psychotropic medications augment these trends by increasing rates of obesity, diabetes, and hyperlipidemia among those treated. Researchers have developed innovative care models aimed at minimizing the disparate health outcomes of patients with serious mental illness. Most strive to enhance access to primary care, but publications on this topic appear almost exclusively in the psychiatric literature. A focus on primary care for the prevention of excess cardiometabolic morbidity and mortality in this population is appropriate, but depends on primary care physicians' understanding of the problem, involvement in the solutions, and collaboration with psychiatrists. We review health outcomes of the seriously mentally ill and models designed to improve these outcomes. We propose specific strategies for Family Medicine clinicians and researchers to address this problem.
众多研究表明,严重精神疾病患者的身体发病率过高且过早死亡。尽管自杀仍是该人群的一个重要死因,但心血管疾病是主要死因。严重精神疾病患者的心血管疾病死亡率是普通人群的2至3倍。这种易感性通常归因于潜在的精神疾病和行为。一些额外的疾病和死亡是由于难以获得和使用优质医疗保健所致。新型精神药物对心脏代谢的负面影响通过增加接受治疗者的肥胖、糖尿病和高脂血症发病率,加剧了这些趋势。研究人员已经开发出创新的护理模式,旨在尽量减少严重精神疾病患者不同的健康结局。大多数模式致力于增加获得初级保健的机会,但关于这一主题的出版物几乎只出现在精神病学文献中。关注初级保健以预防该人群过多的心脏代谢发病率和死亡率是恰当的,但这取决于初级保健医生对该问题的理解、对解决方案的参与以及与精神科医生的合作。我们回顾了严重精神疾病患者的健康结局以及旨在改善这些结局的模式。我们为家庭医学临床医生和研究人员提出了解决这一问题的具体策略。