Kanai Yoshitaka, Matsuda Mitsuhiro, Iwanaga Takayuki, Hashimoto Shigeo, Maeda Yasuhiro, Kanamaru Akihisa, Itagaki Nobuo
Department of Internal Medicine, PL General Hospital, Japan.
Rinsho Ketsueki. 2009 Feb;50(2):113-5.
A 74-year-old man was hospitalized with hypoglossal nerve paralysis and severe great occipital neuralgia. Enhanced MRI of the head showed tumor on the left petrous bone, which compressed the medulla oblongata. Soluble IL-2 receptor was elevated and malignant lymphoma was clinically diagnosed. PET-CT demonstrated a single hot spot on the spleen. After radiation therapy to the lesion on the petrous bone, splenectomy was performed. Pathological findings established a diagnosis of diffuse large B-cell lymphoma. After chemotherapy consisting of rituximab and THP-COP, complete remission was achieved.