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[催乳素对器官型培养中感觉神经元神经突生长的刺激作用]

[The stimulating effect of prolactin on the neurite growth of sensory neurons in an organotypic culture].

作者信息

Chalisova N I, Mel'kishev V F, Akoev G N, Liudyno M I, Kurenkova T Iu

出版信息

Tsitologiia. 1991;33(2):29-31.

PMID:1926570
Abstract

Prolactine was found to promote neurite extension in chick embryo dorsal root ganglia in vitro. This hormone was active at the concentration 10-50 ng/ml provided extensive neurite outgrowth in the bioassay, compared to the control. The liquor from patients with prolactinoma was also found to promote neurite extension. This fact may be used for prolactinoma diagnostics.

摘要

研究发现,催乳素可促进鸡胚背根神经节在体外的神经突延伸。与对照组相比,该激素在10 - 50 ng/ml的浓度下具有活性,能在生物测定中促使神经突大量生长。还发现催乳素瘤患者的脑脊液也可促进神经突延伸。这一事实可用于催乳素瘤的诊断。

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