Kay S
Hum Pathol. 1977 Mar;8(2):224-30. doi: 10.1016/s0046-8177(77)80083-x.
The ultrastructural features of a bronchiolar-alveolar carcinoma of the lung are described wherein the presence of nuclear bodies in many of the tumor cells were noted. Although these bodies are not viral elements, it is surmised that they may be virus associated and consequently possibly related to the etiology of this tumor. A review of the ultrastructural findings in the pulmonary adenomatosis of sheep is presented, and these are compared with those in human disease. Experimental evidence of an infectious agent responsible for human lung carcinomas is discussed, and possible avenues for future investigation are delineated.
本文描述了肺细支气管肺泡癌的超微结构特征，其中注意到许多肿瘤细胞中存在核体。尽管这些核体不是病毒成分，但据推测它们可能与病毒有关，因此可能与该肿瘤的病因有关。本文还介绍了绵羊肺腺瘤病的超微结构研究结果，并将其与人类疾病的结果进行了比较。讨论了导致人类肺癌的感染因子的实验证据，并阐述了未来可能的研究途径。
