Ley S J, Livingston A, Waterman A E
Department of Pharmacology, University of Bristol.
Vet Rec. 1991 Jul 20;129(3):45-7. doi: 10.1136/vr.129.3.45.
Plasma cortisol, prolactin and vasopressin concentrations were measured by radioimmunoassay in blood samples from control and lame sheep. The lame sheep were all suffering from naturally occurring clinical cases of footrot and showed all the behavioural characteristics of chronic pain; they were scored for impairment of gait and pathology of the foot and divided into mild and severely lame groups. The severely lame sheep had increased plasma prolactin and decreased plasma cortisol concentrations. Plasma vasopressin was variable and showed no consistent changes with lameness. The relationships between plasma cortisol, prolactin and vasopressin may be a useful index in the assessment of animals experiencing chronic pain, when taken in conjunction with other measurements.
通过放射免疫分析法测定了对照羊和跛行羊血液样本中的血浆皮质醇、催乳素和血管加压素浓度。跛行羊均患有自然发生的腐蹄病临床病例，并表现出慢性疼痛的所有行为特征；对它们的步态损伤和足部病理进行评分，并分为轻度和重度跛行组。重度跛行羊的血浆催乳素增加，血浆皮质醇浓度降低。血浆血管加压素变化不定，与跛行无一致变化。血浆皮质醇、催乳素和血管加压素之间的关系，与其他测量结果结合起来时，可能是评估经历慢性疼痛动物的有用指标。
