Felsenfeld A D, Schmidt N J
Infect Immun. 1977 Mar;15(3):807-12. doi: 10.1128/iai.15.3.807-812.1977.
Cross-neutralization and complement fixation tests demonstrated the immunological identity of the Delta herpesvirus, the 592S virus, the Liverpool vervet monkey virus, the herpesvirus of patas monkeys, and the Medical Lake macaque virus. These viruses were isolated from diverse outbreaks of varicella-like disease in simians and from various simian species. All of the simian viruses were shown to be related to human varicella-zoster (V-Z) virus, as evidenced by the fact that immunization of monkeys with each of the simian viruses elicited the production of both neutralizing and complement-fixing antibodies to V-Z virus. However, cross-complement fixation tests indicated that the simian viruses are not so closely related to V-Z virus as they are to one another. Varicella or zoster infections in humans produced neutralizing and complement-fixing antibody responses to each of the simian viruses; the responses were more marked in zoster infections than in varicella infections but, in most patients, antibody levels produced to the simian viruses were much lower than those to the homologous V-Z virus.
交叉中和试验和补体结合试验证明了德尔塔疱疹病毒、592S病毒、利物浦绿猴病毒、粗尾猿疱疹病毒和医学湖猕猴病毒的免疫学同一性。这些病毒是从猿猴中不同的水痘样疾病暴发以及各种猿猴物种中分离出来的。所有猿猴病毒都显示与人类水痘-带状疱疹（V-Z）病毒有关，这一事实表明，用每种猿猴病毒免疫猴子会引发针对V-Z病毒的中和抗体和补体结合抗体的产生。然而，交叉补体结合试验表明，猿猴病毒彼此之间的关系并不像它们与V-Z病毒那样密切。人类的水痘或带状疱疹感染会对每种猿猴病毒产生中和抗体和补体结合抗体反应；这些反应在带状疱疹感染中比在水痘感染中更明显，但在大多数患者中，针对猿猴病毒产生的抗体水平远低于针对同源V-Z病毒产生的抗体水平。
