[The contribution of modern biology to a better understanding of disease].

The human disease in its biological foundation must be congruent with the normal processes of the life and explicable by these. The simplified view on disease in the past with the reduction on its biological and physico-chemical course seems to become more and more insufficient and limiting to a comprehensive understanding. The discussion of the concept of disease from the standpoint of the epistomology needs in consequence of the so called new thinking the integrated inclusion of the systems theory, the theory of chaos and the concept of layers by Riedl. Taking this in the consideration a comprehensive understanding of disease is given. This allows to take into account as well its evolutionary conditionality, its human being as its individual, group, population and species specific characteristics. This kind of view emphasizes the necessity to complete the pragmatic reductionism by a comprehensive sight. In the consequence of such a thinking it seems easier to recognize the with the increasing complexity of the living beings emergent laws.