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1995 - 2006年感染人类免疫缺陷病毒的女性中有害饮酒的纵向趋势

Longitudinal trends in hazardous alcohol consumption among women with human immunodeficiency virus infection, 1995-2006.

作者信息

Cook Robert L, Zhu Fang, Belnap Bea Herbeck, Weber Kathleen, Cook Judith A, Vlahov David, Wilson Tracey E, Hessol Nancy A, Plankey Michael, Howard Andrea A, Cole Stephen R, Sharp Gerald B, Richardson Jean L, Cohen Mardge H

机构信息

Department of Epidemiology and Biostatistics, University of Florida, Gainesville, 32607, USA.

出版信息

Am J Epidemiol. 2009 Apr 15;169(8):1025-32. doi: 10.1093/aje/kwp004. Epub 2009 Mar 6.

Abstract

Hazardous alcohol consumption among women with human immunodeficiency virus (HIV) infection is associated with several adverse health and behavioral outcomes, but the proportion of HIV-positive women who engage in hazardous drinking over time is unclear. The authors sought to determine rates of hazardous alcohol consumption among these women over time and to identify factors associated with this behavior. Subjects were 2,770 HIV-positive women recruited from 6 US cities who participated in semiannual follow-up visits in the Women's Interagency HIV Study from 1995 to 2006. Hazardous alcohol consumption was defined as exceeding daily (> or =4 drinks) or weekly (>7 drinks) consumption recommendations. Over the 11-year follow-up period, 14%-24% of the women reported past-year hazardous drinking, with a slight decrease in hazardous drinking over time. Women were significantly more likely to report hazardous drinking if they were unemployed, were not high school graduates, had been enrolled in the original cohort (1994-1995), had a CD4 cell count of 200-500 cells/mL, were hepatitis C-seropositive, or had symptoms of depression. Approximately 1 in 5 of the women met criteria for hazardous drinking. Interventions to identify and address hazardous drinking among HIV-positive women are urgently needed.

摘要

感染人类免疫缺陷病毒(HIV)的女性中存在有害饮酒情况,这与多种不良健康和行为后果相关,但随着时间推移,从事有害饮酒的HIV阳性女性比例尚不清楚。作者试图确定这些女性中有害饮酒的发生率,并找出与这种行为相关的因素。研究对象为从美国6个城市招募的2770名HIV阳性女性,她们在1995年至2006年期间参与了女性机构间HIV研究的半年一次随访。有害饮酒被定义为超过每日(≥4杯)或每周(>7杯)的饮酒建议量。在11年的随访期内,14% - 24%的女性报告过去一年有有害饮酒行为,且有害饮酒行为随时间略有下降。如果女性失业、未高中毕业、最初纳入队列(1994 - 1995年)、CD4细胞计数为200 - 500个/毫升、丙型肝炎血清学阳性或有抑郁症状,她们报告有害饮酒的可能性显著更高。约五分之一的女性符合有害饮酒标准。迫切需要采取干预措施来识别和解决HIV阳性女性中的有害饮酒问题。

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