Hirose G, Kawada J, Tsukada K, Komatsuzaki A, Sharpe J A
Department of Neurology, Kanazawa Medical University, Ishikawa, Japan.
Acta Otolaryngol Suppl. 1991;481:357-60. doi: 10.3109/00016489109131421.
We report an electro-oculographic study (EOG) of upbeat nystagmus and neuroradiological correlations in 4 patients and neuropathological findings in 1 patient. All 4 patients revealed responsible lesions in the lower pontine tegmentum. The EOG data suggest that our patients had a deficit in vertical smooth eye movement balance. The nystagmus stopped or reversed direction during convergence or changes of head position. These EOG findings might be caused by vertical imbalance in the otolithic ocular reflex, superimposed on an imbalanced vestibulo-ocular reflex (VOR), secondary to a damage to the pontomedullary tegmentum.
我们报告了4例患者的上跳性眼球震颤的眼电图研究（EOG）及其神经放射学相关性，以及1例患者的神经病理学发现。所有4例患者均显示脑桥下部被盖部存在责任病灶。眼电图数据表明，我们的患者在垂直性平稳眼球运动平衡方面存在缺陷。眼球震颤在集合或头部位置改变时停止或改变方向。这些眼电图发现可能是由于耳石性眼反射的垂直失衡，叠加在前庭眼反射（VOR）失衡之上，继发于脑桥延髓被盖部损伤。
