肾树突状细胞：最新进展
Renal dendritic cells: an update.
作者信息
Velázquez Peter, Dustin Michael L, Nelson Peter J
机构信息
Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, N.Y., USA.
出版信息
Nephron Exp Nephrol. 2009;111(3):e67-71. doi: 10.1159/000208210. Epub 2009 Mar 10.
Abstract
Discovery into the role of renal dendritic cells (rDCs) in health and disease of the kidney is rapidly accelerating. Progress in deciphering DC precursors and the heterogeneity of monocyte subsets in mice and humans is providing insight into the biology of rDCs. Recent findings have extended knowledge of the origins, anatomy and function of the rDC network at steady state and during periods of injury to the renal parenchyma. This brief review highlights these new findings and provides an update on the study of rDCs.
摘要
对肾树突状细胞（rDCs）在肾脏健康与疾病中作用的探索正在迅速加速。在解读小鼠和人类中DC前体以及单核细胞亚群异质性方面取得的进展，正为深入了解rDCs的生物学特性提供线索。最近的研究结果扩展了我们对稳态下以及肾实质损伤期间rDC网络的起源、解剖结构和功能的认识。这篇简短的综述突出了这些新发现，并提供了关于rDCs研究的最新情况。
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