Britton Robert A, Versalovic James
Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824, USA.
Interdiscip Perspect Infect Dis. 2008;2008:290769. doi: 10.1155/2008/290769. Epub 2009 Feb 4.
Gastrointestinal infections are a major cause of morbidity and mortality worldwide, particularly in developing countries. The use of probiotics to prevent and treat a variety of diarrheal diseases has gained favor in recent years. Examples where probiotics have positively impacted gastroenteritis will be highlighted. However, the overall efficacy of these treatments and the mechanisms by which probiotics ameliorate gastrointestinal infections are mostly unknown. We will discuss possible mechanisms by which probiotics could have a beneficial impact by enhancing the prevention or treatment of diarrheal diseases.
胃肠道感染是全球发病和死亡的主要原因，在发展中国家尤为如此。近年来，使用益生菌预防和治疗各种腹泻病受到青睐。将重点介绍益生菌对肠胃炎产生积极影响的实例。然而，这些治疗方法的总体疗效以及益生菌改善胃肠道感染的机制大多尚不清楚。我们将讨论益生菌通过加强腹泻病的预防或治疗可能产生有益影响的潜在机制。
