Ruzsics Balazs, Gebregziabher Mulugeta, Lee Heon, Brothers Robin L, Allmendinger Thomas, Vogt Sebastian, Costello Philip, Schoepf U Joseph
Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, 25 Courtenay Dr., Charleston, SC 29401, USA.
Eur Radiol. 2009 Aug;19(8):1906-13. doi: 10.1007/s00330-009-1368-8. Epub 2009 Mar 11.
We evaluated an algorithm for automatic selection of the cardiac phase with the least motion for image reconstruction at coronary computed tomography (CT) angiography (CCTA). We analyzed data of 100 patients (49 female, mean age 59 years) who had undergone retrospectively ECG-gated CCTA. Two experienced observers visually identified the most suitable end-systolic and end-diastolic phases using a series of image reconstructions in 5% increments across the RR cycle. The same data were then reconstructed using an automatic phase finding algorithm based on a 4D weighting function of cardiac motion. On average, the algorithm determined the most suitable systolic reconstruction phase at 40.11 +/- 6.29% RR compared with 40.07 +/- 5.58% RR by the human observers (p = NS). The most suitable diastolic phase was found at 72.71 +/- 7.37% RR by the automatic algorithm, compared with 76.43 +/- 6.35% RR by the observers (p < 0.05). No statistically significant difference was found between automatically and visually determined reconstruction phases regarding motion and stair-step artifacts in either systole or diastole (p > 0.05). Thus, there appears to be no relevant difference between an automatic phase finding algorithm and visual selection by experienced observers for determining the phase with the least cardiac motion for CCTA image reconstruction. The use of automatic phase finding may therefore facilitate the performance of cardiac CT and reduce human error.
我们评估了一种算法,用于在冠状动脉计算机断层扫描(CT)血管造影(CCTA)中自动选择运动最少的心动周期时相以进行图像重建。我们分析了100例患者(49例女性,平均年龄59岁)的回顾性心电图门控CCTA数据。两名经验丰富的观察者通过在RR周期内以5%的增量进行一系列图像重建,直观地确定最合适的收缩末期和舒张末期时相。然后使用基于心脏运动的4D加权函数的自动时相查找算法对相同数据进行重建。平均而言,该算法确定最合适的收缩期重建时相为RR间期的40.11±6.29%,而人类观察者确定的为40.07±5.58%RR(p=无统计学意义)。自动算法确定最合适的舒张期时相为RR间期的72.71±7.37%,而观察者确定的为76.43±6.35%RR(p<0.05)。在收缩期或舒张期,自动和直观确定的重建时相在运动和阶梯状伪影方面均未发现统计学显著差异(p>0.05)。因此,对于CCTA图像重建,在确定心脏运动最少的时相方面,自动时相查找算法与经验丰富的观察者进行的直观选择之间似乎没有相关差异。因此,使用自动时相查找可能会促进心脏CT的操作并减少人为误差。