Yang Richard C, Mills Paul K
California Cancer Registry, Public Health Institute, 1815 Bell Street, Sacramento, CA 95825, USA.
Cancer Causes Control. 2009 Aug;20(6):1011-6. doi: 10.1007/s10552-009-9325-z. Epub 2009 Mar 12.
When the Vietnam War ended in 1975, pro-US Laotians (including Lao, Mien, Khmu) were displaced and became refugees in their own native country. Thousands fled to refugee camps in nearby Thailand and were eventually relocated to several Western countries, including the US. A listing of 1,195 Laotian cancer cases were extracted from the California Cancer Registry for diagnosis years 1988-2006. Cancer cases with birthplace coded as "Laos" were included. Proportionate incidence ratios (PIRs) and associated 95% confidence intervals (CI) were calculated for 17 selected cancer sites. The total population of California (all race/ethnic groups combined) was used as the reference. Proportional occurrence of cancers varied by genders and by cancer sites. Laotians in California experienced statistically significantly elevated risks for cancer of the nasopharynx (PIR = 14.8; 95% CI = 10.5-20.1), liver (PIR = 12.6; 95% CI = 10.8-14.6), stomach (PIR = 3.1; 95% CI = 2.4-4.0), cervix (PIR = 1.9; 95% CI = 1.5-2.3), pancreas (PIR = 2.1; 95% CI = 1.5-2.8), oral cavity (PIR = 1.8; 95% CI = 1.4-2.3), lung and bronchus (PIR = 1.4; 95% CI = 1.2-1.7). As found for other Asian subgroups, Laotians, too, have statistically significantly reduced risks for colorectal (PIR = 0.8; 95% CI = 0.6-0.9), colon (PIR = 0.7; 95% CI 0.5-0.9), breast (PIR 0.7; 95% CI = 0.5-0.8), and prostate (PIR = 0.1; 95% CI = 0.0-0.2) cancers. The increased risk found for mostly non-Western types of cancers have implications for culturally responsive cancer control and intervention activities targeting the Laotian population.
1975年越南战争结束后，亲美的老挝人（包括老族、苗族、克木族）被迫背井离乡，在自己的祖国沦为难民。数千人逃到了附近泰国的难民营，最终被重新安置到包括美国在内的几个西方国家。从加利福尼亚癌症登记处提取了1988 - 2006年诊断的1195例老挝癌症病例。出生地编码为“老挝”的癌症病例被纳入研究。计算了17个选定癌症部位的比例发病率（PIR）及相关的95%置信区间（CI）。以加利福尼亚的总人口（所有种族/族裔群体合计）作为参照。癌症的比例发生率因性别和癌症部位而异。加利福尼亚的老挝人患鼻咽癌（PIR = 14.8；95% CI = 10.5 - 20.1）、肝癌（PIR = 12.6；95% CI = 10.8 - 14.6）、胃癌（PIR = 3.1；95% CI = 2.4 - 4.0）、宫颈癌（PIR = 1.9；95% CI = 1.5 - 2.3）、胰腺癌（PIR = 2.1；95% CI = 1.5 - 2.8）、口腔癌（PIR = 1.8；95% CI = 1.4 - 2.3）、肺癌和支气管癌（PIR = 1.4；95% CI = 1.2 - 1.7）的风险在统计学上显著升高。与其他亚洲亚组一样，老挝人患结直肠癌（PIR = 0.8；95% CI = 0.6 - 0.9）、结肠癌（PIR = 0.7；95% CI 0.5 - 0.9）、乳腺癌（PIR 0.7；95% CI = 0.5 - 0.8）和前列腺癌（PIR = 0.1；95% CI = 0.0 - 0.2）的风险在统计学上显著降低。大多数非西方类型癌症风险的增加对针对老挝人群的具有文化适应性的癌症控制和干预活动具有启示意义。
