Teague M W, Glick A D, Fogo A B
Department of Pathology, Vanderbilt University Hospital, Nashville, TN.
Am J Kidney Dis. 1991 Oct;18(4):499-502. doi: 10.1016/s0272-6386(12)80121-1.
Adenovirus (AV) infection usually has a benign course in normal hosts; however, in immunocompromised patients, AV may cause pneumonia, cystitis, or disseminated disease with substantial morbidity and even mortality. Although pulmonic AV involvement is common, infection of the kidney is unusual. The histologic findings previously described include tubular necrosis with interstitial inflammation and glomerulonephritis. We report a case of an AV-induced unilateral mass lesion in the kidney of a patient with Hodgkin's disease (HD) following bone marrow transplantation.
腺病毒(AV)感染在正常宿主中通常病程良性;然而,在免疫功能低下的患者中,AV可能导致肺炎、膀胱炎或播散性疾病,具有较高的发病率甚至死亡率。尽管肺部AV感染很常见,但肾脏感染并不常见。先前描述的组织学表现包括肾小管坏死伴间质炎症和肾小球肾炎。我们报告一例骨髓移植后霍奇金病(HD)患者肾脏中由AV引起的单侧肿块病变病例。