Kolankiewicz Luiz M, Pullman James, Raffeld Mark, Kopp Jeffrey B, Glicklich Daniel
Department of Nephrology.
Department of Pathology , Albert Einstein College of Medicine , New York, NY , USA.
NDT Plus. 2010 Aug;3(4):388-92. doi: 10.1093/ndtplus/sfq024. Epub 2010 Mar 14.
We report an unusual case of adenoviral nephritis in a 45-year-old woman who presented with fever, gross haematuria, acute kidney injury and obstructive uropathy 17 months following renal transplantation. Adenoviral nephritis was confirmed with immunohistochemistry. We identified 10 other published cases of adenoviral nephritis proven by immunohistochemistry. Obstructive uropathy has been reported only once before in a renal transplant recipient with adenoviral nephritis. Contrary to other reports, this case series shows that renal function may not always recover to baseline following the acute adenoviral disease. Adenoviral nephritis should be considered in the renal transplant patient with fever, haematuria, acute kidney injury and hydronephrosis in both the early and late post-transplant periods.
我们报告了一例罕见的腺病毒性肾炎病例，患者为一名45岁女性，在肾移植17个月后出现发热、肉眼血尿、急性肾损伤和梗阻性尿路病。通过免疫组织化学确诊为腺病毒性肾炎。我们还识别出其他10例经免疫组织化学证实的腺病毒性肾炎已发表病例。梗阻性尿路病此前仅在一名患有腺病毒性肾炎的肾移植受者中被报道过一次。与其他报告相反，该病例系列表明，急性腺病毒疾病后肾功能并非总能恢复到基线水平。对于移植后早期和晚期出现发热、血尿、急性肾损伤和肾积水的肾移植患者，均应考虑腺病毒性肾炎的可能性。
