Phelps K R, Ginsberg S S, Cunningham A W, Tschachler E, Dosik H
Department of Medicine, State University of New York Health Science Center, Brooklyn.
Am J Med Sci. 1991 Oct;302(4):224-8. doi: 10.1097/00000441-199110000-00006.
Adult T-cell leukemia/lymphoma (ATLL) was demonstrated postmortem in a 47-year-old woman initially manifesting severe hypercalcemia and a vertebral compression fracture. Hyperinfection with Strongyloides stercoralis preceded the appearance of ATLL by several months and ultimately dominated the terminal course. Although HTLV-I and S. stercoralis commonly infect the same host, only three other cases of concomitant ATLL and hyperinfection have been reported in English. The apparent rarity of this association suggests that immunologic sequelae of ATLL do not predispose to dissemination and multiplication of Strongyloides. Observations pertinent to this conclusion are reviewed.
一名47岁女性尸检时被证实患有成人T细胞白血病/淋巴瘤（ATLL），该患者最初表现为严重高钙血症和椎体压缩性骨折。粪类圆线虫重度感染先于ATLL出现数月，并最终主导了终末期病程。虽然人类嗜T淋巴细胞病毒I型（HTLV-I）和粪类圆线虫通常感染同一宿主，但英文文献中仅报道了另外3例ATLL与重度感染并存的病例。这种关联明显罕见，提示ATLL的免疫后遗症不会促使粪类圆线虫播散和增殖。本文对与该结论相关的观察结果进行了综述。
