Rosenbaum J T, Tammaro J, Robertson J E
Department of Ophthalmology, Oregon Health Sciences University, Portland 97221.
Am J Ophthalmol. 1991 Oct 15;112(4):392-5. doi: 10.1016/s0002-9394(14)76245-2.
Although penetrating trauma is a well-recognized cause of uveitis, the role of nonpenetrating trauma in initiating uveitis is not defined. We analyzed the records of 496 patients seen at the uveitis clinic at our institution. Twenty-four of these 496 patients (4.8%) suspected that the cause of their intraocular inflammation was related to previous nonpenetrating trauma. In contrast, only one of 251 patients (0.4%) attending the general ophthalmology clinic for routine care provided a history of recent trauma or attributed the present ocular complaint to trauma (P less than .02). Patients with posttraumatic uveitis were usually male (19 of 24, 79%), younger (31 +/- 16 years) than the average patient examined in the uveitis clinic, and more likely to have unilateral disease. In ten (42%) of the patients the trauma was work-related. Bilateral inflammation was seen in eight (one third) of the patients and 17 of 28 patients (71%) had a considerable degree of inflammation posterior to the lens. Many patients had an identifiable cause of uveitis such as ankylosing spondylitis, Reiter's syndrome, sarcoidosis, or acute retinal necrosis; but most patients had no known predisposition. The role of nonpenetrating trauma in initiating uveitis has implications for diagnosis and treatment.
尽管穿透性创伤是葡萄膜炎公认的病因，但非穿透性创伤在引发葡萄膜炎中的作用尚不明确。我们分析了在我院葡萄膜炎门诊就诊的496例患者的病历。这496例患者中有24例（4.8%）怀疑其眼内炎症的病因与既往非穿透性创伤有关。相比之下，在251例因常规护理而就诊于普通眼科门诊的患者中，只有1例（0.4%）提供了近期创伤史或将目前的眼部不适归因于创伤（P<0.02）。创伤后葡萄膜炎患者通常为男性（24例中的19例，79%），比葡萄膜炎门诊检查的平均患者年龄小（31±16岁），且更易患单眼疾病。在10例（42%）患者中，创伤与工作有关。8例（三分之一）患者出现双侧炎症，28例患者中有17例（71%）晶状体后有相当程度的炎症。许多患者有可识别的葡萄膜炎病因，如强直性脊柱炎、赖特综合征、结节病或急性视网膜坏死；但大多数患者无已知的易患因素。非穿透性创伤在引发葡萄膜炎中的作用对诊断和治疗有影响。
