Martin Peter R, Arria Amelia M, Fischer Gabriele, Kaltenbach Karol, Heil Sarah H, Stine Susan M, Coyle Mara G, Selby Peter, Jones Hendrée E
Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Am J Addict. 2009 Mar-Apr;18(2):148-56. doi: 10.1080/10550490902772975.
Illicit drug use during pregnancy presents complex clinical challenges, including reducing drug use and treating psychiatric disorders. Pharmacologic treatment of psychiatric disorders in a pregnant woman requires an evaluation of the balance between potential clinical benefit and the risk of potential neonatal consequences. This study describes psychiatric symptoms in 111 opioid-dependent pregnant women and their prescribed psychotropic medications. Hypomania, generalized anxiety disorder and depression were the most common disorders for which psychiatric symptoms were endorsed. Over half of women studied were prescribed some form of psychoactive medication during pregnancy. Pharmacologic vs. non-pharmacologic treatment approaches in this patient population are discussed.
孕期使用非法药物带来了复杂的临床挑战，包括减少药物使用以及治疗精神障碍。对孕妇精神障碍进行药物治疗需要评估潜在临床益处与潜在新生儿后果风险之间的平衡。本研究描述了111名阿片类药物依赖孕妇的精神症状及其所开具的精神药物。轻躁狂、广泛性焦虑障碍和抑郁症是最常被认可存在精神症状的疾病。超过半数的研究对象在孕期被开具了某种形式的精神活性药物。本文还讨论了该患者群体的药物治疗与非药物治疗方法。
