Raghavendra A G, Gajendragad M R, Sengupta P P, Patil S S, Tiwari C B, Balumahendiran M, Sankri V, Prabhudas K
Department of Diagnostic Medicine / Pathobiology, # 308, Coles Hall, KSUCVM, Kansas State University, Manhattan, Kansas 66506-5606, USA.
Rev Sci Tech. 2008 Dec;27(3):861-7. doi: 10.20506/rst.27.3.1838.
This paper presents the results of a seroepidemiological study carried out between July 2006 and March 2007 to detect the presence of antibodies to peste des petits ruminants (PPR) virus in randomly collected serum samples from sheep and goats in southern peninsular India. The authors used a competitive enzyme-linked immunosorbent assay with a monoclonal antibody developed against a neutralising epitope of the haemagglutinin (HA) protein of the virus. A total of 1,492 sheep sera and 2,068 goat sera collected from the six southern Indian states were screened. It was determined that 41.35% of the sheep sera and 34.91% of the goat sera were positive for the presence of antibody. The study indicated an extensive endemicity of the disease in these states, which is attributed to the agro-climatic conditions and the migration of livestock.
本文介绍了2006年7月至2007年3月期间开展的一项血清流行病学研究结果,该研究旨在检测从印度半岛南部随机采集的绵羊和山羊血清样本中是否存在小反刍兽疫(PPR)病毒抗体。作者采用了一种竞争性酶联免疫吸附测定法,使用针对该病毒血凝素(HA)蛋白中和表位开发的单克隆抗体。对从印度南部六个邦采集的1492份绵羊血清和2068份山羊血清进行了筛查。结果确定,41.35%的绵羊血清和34.91%的山羊血清抗体呈阳性。该研究表明该疾病在这些邦广泛流行,这归因于农业气候条件和牲畜的迁移。