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[局部和多焦视网膜电图在糖尿病视网膜病变诊断中的应用]

[Loal and multifocal electroretinography in the diagnosis of diabetic retinopathy].

作者信息

Arakelian M A, Mansurina N B, Shamshinova A M

出版信息

Vestn Oftalmol. 2009 Jan-Feb;125(1):36-9.

Abstract

The paper gives the results of electroretinography (ERG) in 38 patients (73 eyes) with type 2 diabetes mellitus at different stages of diabetic retinopathy (including in diabetic macular edema). The reductions in the macular ERG (M-ERG) amplitude parameters and in the retinal density of bioelectrical activity and the decreased amplitude and longer latency of multifocal ERG (mfERG) N1 and P1 components evidence the involvement of the retinal macular region into the pathological process and the magnitude of these changes depends on the presence of imaged macular edema. Despite the certain limitations of mfERG, assessment of the topography of retinal bioelectrical activity in the central field of vision is an important supplement to M-ERG results and may be a prognostic criterion for the development of a pathological process and its extent.

摘要

该论文给出了38例2型糖尿病患者(73只眼)在糖尿病视网膜病变不同阶段(包括糖尿病性黄斑水肿)的视网膜电图(ERG)结果。黄斑区视网膜电图(M-ERG)振幅参数、生物电活动视网膜密度的降低以及多焦视网膜电图(mfERG)N1和P1成分振幅降低、潜伏期延长,证明视网膜黄斑区参与了病理过程,且这些变化的程度取决于成像黄斑水肿的存在。尽管mfERG存在一定局限性,但评估中央视野视网膜生物电活动的地形图是对M-ERG结果的重要补充,可能是病理过程发展及其程度的预后标准。

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