Horita H, Uchida E, Maekawa K
Department of Pediatrics, Jikei University School of Medicine, Tokyo, Japan.
Brain Dev. 1991 May;13(3):200-2. doi: 10.1016/s0387-7604(12)80032-5.
Four girls with childhood absence epilepsy with several seizures every day were investigated using an ambulatory cassette EEG. Recordings were started at about 6 pm, and were run continuously for about 22 hours. We studied only the regular and symmetrical 3 Hz spike-wave discharges of at least 5 seconds duration, which are quite similar to or identical with those found in the clinical seizures. Regular spike-wave discharges occurred frequently during wakefulness in 2 cases and during sleep in the other 2 cases: in the latter, they occurred rarely during wakefulness. During wakefulness, we did not find a special time zone in which regular spike-wave discharges were facilitated; during nocturnal sleep, however, they were concentrated in the last third. The rate of regular spike-wave discharges per hour was the highest during stage 1, low during stages 2 and REM, and zero during stage 3 + 4. Average duration of regular spike-wave discharges was the longest during wakefulness in most cases, and shortest during stage 2 in all the cases.
对4名每天有多次发作的儿童失神癫痫女孩进行了动态盒式脑电图检查。记录于下午6点左右开始，持续约22小时。我们仅研究持续至少5秒的规则且对称的3Hz棘慢波放电，其与临床发作中发现的放电非常相似或相同。2例患者在清醒时频繁出现规则棘慢波放电，另外2例在睡眠时出现：在后者中，清醒时很少出现。清醒时，我们未发现规则棘慢波放电易化的特定时间段；然而，夜间睡眠时，它们集中在最后三分之一时间段。每小时规则棘慢波放电率在第1阶段最高，在第2阶段和快速眼动期较低，在第3 + 4阶段为零。大多数情况下，规则棘慢波放电的平均持续时间在清醒时最长，在所有病例中第2阶段最短。
