Filho João Bortoletti, Nardozza Luciano Marcondes Machado, Araujo Júnior Edward, Rolo Liliam Cristine, Nowak Paulo Martin, Guimarães Filho Hélio Antonio, Moron Antonio Fernandes
Department of Obstetrics, São Paulo Federal University (UNIFESP), São Paulo, SP, Brazil.
J Perinat Med. 2009;37(4):380-5. doi: 10.1515/JPM.2009.050.
Assess vascular indices of 7-10 week embryos using three-dimensional power Doppler (3DPD) and correlate them with the crown-rump length (CRL).
This cross-sectional study included 65 healthy pregnancies between 7 and 10 weeks. The three-dimensional volume of the embryo was obtained using an endocavitary volumetric transducer and the VOCAL (Virtual Organ Computer-aided Analysis) method, with a 12 degree rotation angle and 15 sequential planes. The vascularization (VI), flow (FI) and the vascular and flow (VFI) indices were obtained using 3DPD and the mean, median, standard deviation, maximum and minimum values were calculated for each gestational age. Pearson's correlation coefficient (r) was used to evaluate the correlation between vascular indices and CRL.
The VI ranged from 0.77 to 41.67, mean 14.68 (+/-8.60), the FI went from 25.71 to 139.50, mean 90.61 (+/-21.51) and the VFI from 0.20 to 81.57, mean 15.69 (+/-12.42). The correlation between CRL and all 3D power Doppler vascular indices was low (VI - r=-0.073, P=0.566; FI - r=0.173, P=0.168 and VFI - r=-0.004, P=0.974).
3D power Doppler vascular indices in 7-10 week embryos do not correlate with CRL.
使用三维能量多普勒（3DPD）评估7-10周胚胎的血管指数，并将其与头臀长（CRL）相关联。
这项横断面研究纳入了65例7至10周的健康妊娠。使用腔内容积探头和VOCAL（虚拟器官计算机辅助分析）方法获取胚胎的三维容积，旋转角度为12度，共15个连续平面。使用3DPD获取血管化（VI）、血流（FI）以及血管和血流（VFI）指数，并计算每个孕周的均值、中位数、标准差、最大值和最小值。采用Pearson相关系数（r）评估血管指数与CRL之间的相关性。
VI范围为0.77至41.67，均值为14.68（±8.60）；FI范围为25.71至139.50，均值为90.61（±21.51）；VFI范围为0.20至81.57，均值为15.69（±12.42）。CRL与所有3D能量多普勒血管指数之间的相关性较低（VI - r = -0.073，P = 0.566；FI - r = 0.173，P = 0.168；VFI - r = -0.004，P = 0.974）。
7-10周胚胎的3D能量多普勒血管指数与CRL不相关。
