Doran A L, Morden W E, Dunn K, Edwards-Jones V
School of Biology, Chemistry and Health Science, Manchester Metropolitan University, Manchester, UK.
Lett Appl Microbiol. 2009 Apr;48(4):387-92. doi: 10.1111/j.1472-765X.2009.02552.x.
To determine whether essential oil (EO) vapours could reduce surface and airborne levels of bacteria including methicillin-resistant Staphylococcus aureus (MRSA).
The antibacterial activity of geranium and lemongrass EO individually and blended were evaluated over a range of concentrations by direct contact and vapour diffusion. The EO were tested in vitro against a selection of antibiotic-sensitive and -resistant bacteria, including MRSA, vancomycin-resistant Enterococci (VRE), Acinetobacter baumanii and Clostridium difficile. An EO blend containing lemongrass and geranium was used to formulate BioScent that was dispersed into the environment using the ST Pro machine. The effects were variable depending on the methods used. In a sealed box environment, MRSA growth on seeded plates was reduced by 38% after 20 h exposure to BioScent vapour. In an office environment, the ST Pro machine dispersing BioScent effected an 89% reduction of airborne bacteria in 15 h, when operated at a constant output of 100%.
EO vapours inhibited growth of antibiotic-sensitive and -resistant bacteria in vitro and reduced surface and airborne levels of bacteria.
Results suggest that EO vapours, particularly Bioscent, could be used as a method of air disinfection.
确定香精油（EO）蒸汽是否能降低包括耐甲氧西林金黄色葡萄球菌（MRSA）在内的细菌的表面和空气传播水平。
通过直接接触和蒸汽扩散，在一系列浓度范围内评估了天竺葵和柠檬草EO单独及混合后的抗菌活性。这些EO在体外针对一系列抗生素敏感和耐药细菌进行了测试，包括MRSA、耐万古霉素肠球菌（VRE）、鲍曼不动杆菌和艰难梭菌。一种含有柠檬草和天竺葵的EO混合物被用于配制BioScent，并使用ST Pro机器将其分散到环境中。效果因使用的方法而异。在密封箱环境中，接种平板上的MRSA在暴露于BioScent蒸汽20小时后生长减少了38%。在办公室环境中，当以100%的恒定输出运行时，ST Pro机器分散BioScent在15小时内使空气中的细菌减少了89%。
EO蒸汽在体外抑制了抗生素敏感和耐药细菌的生长，并降低了细菌的表面和空气传播水平。
结果表明，EO蒸汽，特别是BioScent，可作为一种空气消毒方法。
