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假丝酵母菌属(Pseudallescheria boydii)导致的溺死相关性致命真菌性动脉瘤。

Fatal mycotic aneurysm caused by Pseudallescheria boydii after near drowning.

机构信息

Institut für Rechtsmedizin, Universitätsklinikum Jena, Jena, Germany.

出版信息

Int J Legal Med. 2010 May;124(3):243-7. doi: 10.1007/s00414-009-0336-9. Epub 2009 Mar 18.

Abstract

Pseudallescheria boydii is a rare cause of mycotic infection. Factors predisposing to systemic infection include traumas, immunosuppression, and near drowning. We report a case of multiple aneurysms caused by this hyalohyphomycete, occurred after near drowning. The car driven by a 53-year-old woman plunged into a canal in The Netherlands. After a 20-min-long submersion, the woman was rescued. At hospital, a severe aspiration of muddy water and a mycotic pneumonia were diagnosed. Despite the immediate prescription of a long-term antimycotic therapy and the initial good response, the patient died 4 months later. The autopsy showed a mycotic aneurysm of the abdominal aorta and multiple ruptured mycotic aneurysms of the circle of Willis with fatal subarachnoid bleeding.

摘要

毕赤酵母是一种罕见的真菌感染病原体。易导致系统性感染的因素包括外伤、免疫抑制和溺水等。我们报告了一例因该类霉菌引起的多发性动脉瘤病例,该患者发生在溺水后。一辆汽车坠入荷兰的一条运河,一名 53 岁的女性被困在车中。20 分钟后,该女子被救出。在医院,患者被诊断为严重吸入泥水和霉菌性肺炎。尽管立即给予长期抗真菌治疗和初始治疗效果良好,但患者在 4 个月后死亡。尸检显示患者腹主动脉有真菌性动脉瘤,Willis 环有多个破裂的真菌性动脉瘤,并伴有致命性的蛛网膜下腔出血。

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